Clinical Evidence

Curcumin and piperine supplementation and recovery following exercise-induced muscle damage: a randomized controlled trial
J Sports Sci Med.2017;16(1):147–153. PMID: 28344463
Curcuminoids are highly recommendable sports nutrition supplements since they provide support in various health aspects of the sport viz., they help to maintain healthy joints by reducing the inflammatory responses at the bone joints and thus helping athletes for the free movements. Along with protection against inflammation, they also work to improve muscle recovery thus helping the athletes in maintaining muscle tone and flexibility. They act to improve the blood circulation which could help the athlete during rigorous exercise where proper blood circulation is required. They are potent antioxidant agents and thus help to maintain the antioxidant balance after the intense exercise.

This study aimed to analyze the effects of oral consumption of curcumin and piperine in combination with the recovery kinetics after exercise-induced muscle damage.


The study was conducted in sixteen elite level rugby players with weekly training volume based on rugby and gym training. Concentric and isometric peak torque for the knee extensors, one leg 6 seconds sprint performance on a non-motorized treadmill, countermovement jump performance, blood creatine kinase concentration, and muscle soreness were assessed immediately after exercise, then at 24h, 48h and 72h post-exercise.

  • Exercise negatively affected the concentric peak torque for the knee extensors, the one leg 6 seconds sprint performance, and the countermovement jump performance in the 48h following the exercise, the effect was also evident in the increased levels of creatine kinase level 72h after the exercise
  • Twenty-four hours post-exercise, the reduction (from baseline) in sprint mean power output was moderately lower in the curcumin-treated group compared to the placebo group

Curcumin and piperine supplementation attenuated some, but not all, aspects of muscle damage.